A rare mutation in two genes was associated with the risk of early heart attacks in life. "An analysis of more than 9,000 genomes revealed that changes in the low-density lipoprotein receptor gene (LDLR) and in the apolipoprotein A-V (APOA5) gene were linked with elevated levels of plasma LDL cholesterol and plasma triglycerides." http://www.cardiocarenaturally.com/wp-content/uploads/2012/04/heartattackstroke.jpg
The results that was published on December 10 in Nature, says the issue with
with triglyceride metabolism, along with high LDL cholesterol, may be the cause of early heart attacks in life.
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